Tuesday, 1 October 2024

08:30 | Arrival and Registration

09:00 – 09:30

Welcome & Short presentation of the three Clusters of Excellence

Resolving Infection Susceptibility
Reinhold Förster, Hannover Medical School, Germany

Balance of the Microverse
Kirsten Küsel, University of Jena, Germany

Controlling Microbes to Fight Infections
Andreas Peschel, University of Tübingen, Germany

09:30 – 12:00

Antimicrobial Resistance and New Solutions

Chair: Heike Brötz-Oesterhelt & Samuel Wagner (CMFI)

09:30
Fighting Microbes with Microbes – Decolonization Strategies for MDR Bacteria
Maria Vehreschild, Frankfurt University Hospital, Germany

09:55
Mining Bacterial Genomes for Novel Antibiotics
Nadine Ziemert, CMFI, University of Tübingen, Germany

10:20 – 11:10 | Coffee break

11:10
Assault, Siege, Trojan Horses or Gentle Disarmament: Four Molecular Strategies to Fight Bacterial Infections
Mark Brönstrup, Leibniz University Hannover, Germany

11:35
Novel avenues in target-based anti-infective drug discovery
Anna Hirsch, Helmholtz Institute for Pharmaceutical Research Saarland, Germany

12:00 – 13:30 | Lunch

13:30 – 15:35

Microbial Community Resilience

Chair: Hannes Link (CMFI) & Rosalind Allen (Microverse)

13:30
Microbial Community Resilience: Insights into Gut Health and Clinical Implications
Ulrike Löber, Max Delbrück Center for Molecular Medicine, Berlin, Germany

13:55
Gut microbiome assembly in extremely premature infants and implications for gutbrain- axis development
David Berry, University of Vienna, Austria

14:20
Natural Products from Interacting Microorganisms and Ancient Microbiomes
Pierre Stallforth, Microverse, University of Jena and Leibniz-HKI, Jena, Germany

14:45
Microbiome resistance and resilience in response to compound disturbances
Laurent Philippot, INRAE Dijon, France

15:10
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution
Hagay Enav, CMFI, Max Planck Institute for Biology, Tübingen, Germany

15:35 | End of Scientific Part Day 1, Stay-Together-Coffee

15:45 | Group photo of all participants in front of the Futurium

18:30 – 20:00

Public evening with Fishbowl discussion (in German language)

Infektionsforschung im Dienste der Gesundheit:
Ein Dialog zwischen Wissenschaft, Gesellschaft & Politik

Wednesday, 2 October 2024

09:00 – 12:40

Infection Susceptibility

Chair: Thomas Schulz & Gesine Hansen (RESIST)

09:00
Broad-spectrum RNA antiviral inspired by ISG15 deficiency
Dusan Bogunovic, Columbia University Medical Center, New York City, NY, USA

09:25
Regulation of the Varicella Zoster Virus latent-to-lytic switch
Dan Depledge, RESIST, Hannover Medical School, Germany

09:50
Antimicrobial resistance crisis: the microbial growth conjecture
Wolf-Dietrich Hardt, ETH Zurich, Switzerland

10:15 – 11:00 | Coffee break

Chair: Lars Dölken & Dorothee Viemann (RESIST)

11:00
Integrated longitudinal multiomic immune profiling of sepsis
Manu Shankar-Hari, Centre for Inflammation Research, University of Edinburgh, Scotland

11:25
The dysbiotic gut microbiome as reservoir for infection and inflammation in immunocompromised hosts
Christoph Stein-Thoeringer, CMFI, University Hospital Tübingen, Germany

11:50
Integrative Deep Immune Phenotyping of the Elderly Immune System
Lennart Riemann, RESIST, Hannover Medical School, Germany

12:15
Metabolic adaptation as a defence strategy against infection
Miguel Soares, Instituto Gulbenkian de Ciência, Oeiras, Portugal

12:40 – 14:00 | Lunch

14:00 – 15:15

Microbiome & Health

Chair: Ilse Jacobsen & Diana Dudziak (Microverse)

14:00
An ecological perspective on infectious disease: The “Hormesis” principle revisited
Michael Bauer, Microverse, Jena University Hospital, Germany

14:25
Drug-Microbiome Dynamics: Implications for Host Health
Lisa Maier, CMFI, University Hospital Tübingen, Germany

14:50
Insights into the mutual relationship between host and microbiota in early life and its impact on the development of health and disease
Dorothee Viemann, RESIST, Hannover Medical School, Germany

15:15

Final Discussion / Concluding Remarks

15:30 | Departure